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1. Materials Compatibility :
Between Fuel and Coolant
Fuel-coolant chemical reactions, source term release from fuel to coolant
Between Fuel and Cladding
Fuel-cladding chemical interaction (FCCI) is one of the major cladding degradation of advance metallic fuel because of the chemical reactions between nuclear fuel/fission products and stainless steel cladding
Between Coolant and Cladding/Structural Materials
Material degradation and corrosion by coolant, for example, Nickel-based alloys can not be used as structrural materials for liquid-lead/lead-bismuth-cooled reactor because the high solubility of Ni in the liquid metal/alloy
Between Fuel Pin Gap materials and Fuel
Liquid lead can not be used as gap material for oxide fuel, because of the transfer of oxygen